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Neurodegenerative diseases often disrupt neuromodulatory pathways, further impairing cognitive and motor functions

These natural gut dwellers have been used as probiotics to treat diarrhea and ulcerative colitis

A lower Firmicutes/Bacteroidetes ratio (142), reduced counts of Lactobacillaceae (143), and altered abundance of several genera have been reported (144) including Eggerthella , Klebsiella , Flavonifractor , Lachnospiraceae (145, 146), Prevotella , Eubacterium, and Rhodococcus were significantly enriched, whereas Pseudobutyrivibrio and Dialister were decreased in SLE patients (147)