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Its pathogenesis is thought to involve various factors, including insulin resistance, lipotoxicity, gut/nutrient-derived signals, adipocytokines, oxidative stress, and genetic factors

Introduction Oxidative stress results when there is a disturbance in normal cellular and molecular function as a result of an imbalance between the production of various oxidizing chemical species (pro-oxidants) and natural antioxidant ability of cells in favour of the former

For example, 10 antibodies (IgG-A, B, G, H, I, J, N, O, P, and Q) were protected from irreversible aggregations when they were prepared by the alkaline wash method

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