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10.1016/j.bbr.2019.111978 48 ZhangY.ChenY.QuH.WangY

Shalita et al 41 found that patients with inflammatory acne showed significant improvement in acne severity and appearance when a combination of nicotinamide, azelaic acid, pyridoxine, copper, and folic acid was added to existing acne regimens at both four and eight week follow up