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It is important to highlight the variability of clinical data

208 The local release of Cu ions around rat carotid arteries has been shown to promote the thickening of the neointima and the generation of arteriosclerotic lesions in response to vascular injury, 209 whereas the use of Cu chelators exhibit inhibitory effects on vascular inflammation, the development of atherosclerotic lesions, and neointimal formation in response to vascular injury in ApoE knockout mice

HUBERMAN: It does, however, stimulate the melanocytes of the skin, so it leads to tanning or darkening of the skin

One study found that utilizing a vitamin C supplement helped increase glutathione levels in red blood cells by as much as 47%, while another study determined that vitamin C supplementation helped increase glutathione levels in white blood cells by as much as 18%