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This upregulation leads to an increased expression of lipogenic genes, including sterol regulatory element-binding proteins (SREBP1c) and diacylglycerol acyltransferase-2 (DGAT2), which suggests that miR-370 provides a further point of regulation of this pathway 86

Ketamine, a dissociative anesthetic that blocks central NMDA-R, produces transient increases of DA and acute psychotomimetic effects, including NS (Pomarol-Clotet et al., 2006) and it was used to explore the hypo-glutamatergic and DA cortical hypotheses of SCZ (Pomarol-Clotet et al., 2006