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These tests may include a stool analysis, breath test, nutrigenetic data (eg, celiac disease markers), and urine organic acids, all of which, in the authors experience in 20-plus years of practice, can provide information on gut metabolites that impact neurotransmission and immune activation.13 Oxidative Stress Moreover, an association between mental disorders and markers of oxidative stress has been reported in the literature

KEGG enrichment analysis further revealed that these genes were broadly involved in inflammation- and immune-related pathways, including the IL-17 signaling pathway and FoxO signaling pathway ( Figure 3D )