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At least 1000 binucleated cells were counted at 400X magnification for each sample and micronuclei were determined

Chang K, Senzer N, Soetikno R, Swisher SG , Reid T, Mauer A, Vokes E, Pinto H, Chak A, Forastiere A

Functionally, impaired intestinal barrier integrity leads to increased translocation of microbe-associated molecular patterns (MAMPs) into the portal circulation 78