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Noteworthy, the administration of DHA (daily doses of 300 mg/kg) combined with T3 (0.05 mg/kg) to rats increased significantly the content of RVD1 and RVD2 in the liver, but left unchanged that of RVE1 and RVE2, indicating a synergistic effect compared to treatment with DHA alone and T3 alone (118)

These findings support the potential of ALC as both a biomarker and a therapeutic agent in mood disorders