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The STAR gene-counts for each alignment were analyzed for differentially expressed genes using the R package DESeq2 (version 1.32.0) 56 using a generalized linear model

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These actions comprise feeling helpless and anhedonia, two hallmarks of depression symptoms (140, 141)

Indeed, lipid peroxidation products [56], protein carbonylation [34, 43, 50], and DNA oxidation [112, 113] are all increased in various cardiac disease states and are mitigated with MAO-A/B inhibition