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FSP1 can inhibit ferroptosis by reducing ubiquinone or CoQ to ubiquinone or CoQH 2 on the cell membrane, with the latter functioning as an antioxidant that trap radicals and thus prevents lipid peroxidation, thereby preventing ferroptosis (Fig

In this study, we aimed to confirm iron imbalance in a larger cohort of AMD patients and assess its correlation with disease stage

Lysine decarboxylase expression by Vibrio vulnificus is induced by SoxR in response to superoxide stress

106 HIF signaling pathway Hypoxia-inducible factors (HIFs), consisting of an oxygen-sensitive subunit and a constitutively expressed HIF-1 subunit, are major regulators of adaptive responses to hypoxia and directly activate the expression of multiple target genes to maintain cellular oxygen homeostasis