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Supplementary file1: Effects of Tat and/or cocaine on cell viability and microglia morphology in primary cortical cultures (a) Boxplots showing the percentage of dead/apoptotic cells in primary cortical cultures treated with Tat (1, 6, or 60 ng/mL) for 48 h and/or cocaine (10 or 25 M) for an additional 24 h

These compounds not only provide surface-level nutrition but also influence cellular pathways to enhance cutaneous texture, firmness, and resilience

Vitamin C status and serum lipids

For general background on how investigational peptides are evaluated for safety, the National Institutes of Healths overview of how experimental compounds move through clinical evaluation illustrates why oversight matters at every stage