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*Correspondence: Xingsheng Wang, [email protected] Lai, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Rather than relying solely on appetite suppression, emerging therapies aim to address the complex hormonal systems governing energy balance and metabolism

The film's title refers to the initiation ritual of having to kill someone to enter a gang and, on the reverse end, not being able to leave the gang unless killed