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Macone AB, Caruso BK, Leahy RG, Donatelli J, Weir S, Draper MP, et al

Electrophysiological studies examining the excitability of neurons and the inhibitory effects of GABAergic synaptic neurotransmission in the central nucleus of the amygdala (CeA) of homozygous IL6 transgenic mice showed enhanced excitability of the CeA neurons

All compounds (except 3-methyladenine and chloroquine, which were diluted in water) were diluted in DMSO at 250 times the final highest test concentration, and aliquoted across a 384-well plate (Greiner, Monroe, N.C.)