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Carotenoids, including lutein, neoxanthin and -carotene, are important compounds found in broccoli that exhibit lipophilic antioxidant and immunomodulatory activities

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A unifying feature is their ability to mitigate oxidative stressfor example, many flavonoids, alkaloids, and saponins activate the Nrf2/ARE pathway, upregulating endogenous antioxidant enzymes (such as superoxide dismutase and glutathione peroxidase) to neutralize excess reactive oxygen species (Wang Q

The compound has been in pre-clinical investigation for decades