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It can damage the structure of lipid membranes, thereby significantly impacting normal cellular functions

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When you swallow a capsule, that compound must: Wait for the capsule shell to dissolve in stomach acid Survive exposure to gastric acid (pH 1.53.5) without peptide bond cleavage Then be absorbed through the intestinal wall into circulation The problem: gastric acid and digestive enzymes are specifically designed to break peptide bonds which is exactly what glutathione is made of

doi: 10.1016/j.molmed.2020.11.003 64 CapalboAHoffmannERCimadomoDUbaldiFMRienziL