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Ferroptosis activation contributes to the formation of skin lesions in psoriasis vulgaris

Concurrently, substantial preclinical research is exploring other delivery platforms and strategies

Histone acetylation is associated with transcriptional activation and is thus an activation mark, as acetylation neutralizes the positive charge of lysine residues and causes the weakening of DNA and histone interactions leading to looser chromatin

TLR3 is activated by double-stranded DNA in the endosomal compartment, whereas TLR4 can sense the extracellular bacterial lipopolysaccharide (LPS) and then transport to the endosomal compartment