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That small molecular size is the defining advantage: these peptide fragments can cross the blood-brain barrier and interact directly with neurons, something that most endogenous neurotrophic factors cannot do on their own

In another study, Shoval et al applied surface-functionalized CDs (8 nm in size) to successfully penetrate ocular including epithelial layer, cornea, eye cavity and lens

However, the sublingual daily dosing pattern continues to provide some buffer against the most severe symptoms

Researchers who track their metabolic peptide protocols carefully will recognize this as the kind of variable that demands close monitoring rather than assumption