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A similar compound, S-antigen transportinhibiting oligonucleotide polymers (STOPS), which is a locked nucleic acid-modified version of a NAP, is no longer in development due to the minimal effect on HBsAg levels [73]

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In Hashimotos thyroiditis (HT), major sources of oxidative stress include misfolded proteins, dysbiosis and molecular mimicry, self-tolerance defects linked to AIRE gene dysfunction, and irregularities in thyroid protein folding (da Silva et al