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13 Another study, comparing oral and sublingual administration of a complex of B12, folate and vitamin B6 also found no significant differences in effect on homocysteine between the two modes of administration

To address the compounds mechanisms of action, they were evaluated against various phlogistic mediators, including histamine, bradykinin, leukotrienes, and prostaglandins, to confirm the anti-inflammatory pathway of the most potent synthesized compound