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Despite the absence of codified guidelines, BTX-A has been applied from the early 1990s for the treatment of asymmetries caused by FNP, with promising results and improvements in quality of life [10]

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[284] findings that heat treatment can modify silver nanoparticles geometrical shape, altering their emitted light spectrum wavelength, help put together the most robust explanation so far as to why clinical argyria provisional resolution, at least, can be obtained despite silver persistence in the skin and emphasizes the need not discard the possibility of argyria relapse even with silver exposure discontinuation

doi: 10.1006/jmcc.2002.2082