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EC 2.7.1.105), which catalyzes the formation of fructose 2,6-bisphosphate (F2,6BP) from fructose 6-phosphate

Treatments in these co-cultures included PBS as a control, FOXO4-DRI at 50 M, hydrogen peroxide (H2O2) at 50 M to induce senescence, and a combination of H2O2 with FOXO4-DRI