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Thus phenols are oxidized to phenoxy radicals, which participate in reactions where polymers and oligomers are produced that are less toxic than phenols

Carrillo JA & Benitez J (2000) Clinically significant pharmacokinetic interactions between dietary caffeine and medications

This effect may be due to spike protein inducing negative mitochondrial membrane potential, increasing intracellular calcium, and increasing levels of reactive oxygen species (ROS)