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40 Blockade of the AT 1 receptor elicited increases in RBF, indicating a role of Ang II in maintaining renal vascular tone

It was discovered more than 30 years ago, and in all that time, not one controlled human trial of it has been published

A patient with a serious non-healing musculoskeletal injury, conventional options exhausted, full informed consent, ideally inside a registered investigational protocol with structured safety monitoring