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Epigenetic Upregulation of HGF and c-Met Drives Metastasis in Hepatocellular Carcinoma

Recently, researchers characterized a translocation involving histone demethylase KDM5A that resulted in fusion of the H3K4me3-binding PHD finger of KDM5A to the transcriptional activator NUP98, a common leukemia translocation partner, in an acute myeloid leukemia patient (Islam et al