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Studies have now confirmed that dysregulation of autophagy results in the accumulation of pathologic proteins and/or damaged organelles, as is commonly observed in PD 16

Common side effects Nausea Diarrhea Sweating Tremors Trouble sleeping Headache Fatigue Sexual side effects (low libido, difficulty reaching orgasm) Overdose symptoms Headache Drowsiness Blurred vision Fever Convulsions Slow or fast heart rate Coma Insomnia Nausea and vomiting Confusion Serious overdose symptoms Seizures Hallucinations Cardiovascular toxicity Suicidal thoughts Kidney failure Serotonin syndrome An SSRI overdose can trigger serotonin syndrome, a potentially fatal buildup of serotonin

They belong to the group of zinc-dependent matrix metalloproteinases (MMPs), which bind zinc ions to the catalytic site for their activation, forming coenzymes

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