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J Neurochem 2008

Pulipati S, Puttagunta SB, S KV, et al

With regard to NF-B signaling, bortezomib, the first FDA-approved proteasome inhibitor for multiple myeloma, exerts part of its antineoplastic effects through a pharmacological mechanism that targets the NF-B signaling pathway

Some of the surfactant components, such as unsaturated and alkyl phospholipids, have been proposed to act as antioxidants, therefore reducing the exposure of cell membranes to ROS