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Numerous studies have indicated that in scenarios of iron overload, there is an increase in mitochondrial stress, which results in mitochondrial fragmentation and a disruption of the fission and fusion [68, 130]

2 depicts the structural interplay of the writer-eraser-reader system, demonstrating how these enzymes coordinate to translate intracellular lactate levels into precise gene expression outcomes

The researchers also did not directly account for treatment duration or adherence, both of which are known to influence long-term outcomes