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After endocytosis into cancer cells, these NPs partially released Qu that downregulated the expression of heat shock protein 70, in turn allowing for LTPTT

In contrast, Iwata et al

In the last decade, studies on the condition of BBB in neurodegenerative diseases, including ALS, have demonstrated the presence of vascular disruption, a condition that could theoretically favour the entry of drugs into brain regions affected by neurodegeneration