nac apap overdose mechanism glutathione Acetaminophen Toxicity / Poisoning 5️⃣ Antidote: NAC (N-acetylcysteine) NAC
5 Antidote: NAC (N acetylcysteine) NAC replenishes glutathione, restoring the ability to detoxify NAPQI. It's lifesaving if given early. Example: Hospitals use NAC as the standard treatment for APAP overdose. Acetaminophen Toxicity Core EM Acetaminophen metabolism Drug Induced Liver Injury: Clinical Evidence of N Acetyl Cysteine Protective Effects PMC
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