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In the airspace, this high glutathione concentration defends the lung against endogenously produced oxidants as well as environmental oxidants

Along with the presence of high- and low-abundant microbes, the maintenance of the intestinal epithelial barrier is further maintained by critical players, including immune cells (mononuclear macrophages, T-cells, and innate lymphoid cells), enteric glial cells (EGCs), and the intrinsic/extrinsic enteric-associated-neurons (iEANs/eEANs) of the ENS (Muller et al., 2020b)

Methionine sulfoxide is an oxidation product of methionine

As discussed above, a possible reason for this could be that the O- demethylation reaction catalyzed by VanAB produces formaldehyde as a side product, which has been previously suggested to cause a redox imbalance and energy limitation in P