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& Nilges, M

MLO Targeting: The optimized sensor (miniGrx1-roGFP2) with a 20-amino-acid linker was targeted to specific MLOs (nucleoli, stress granules, p-bodies, nuclear paraspeckles, and Cajal bodies) and their surrounding environments (cytosol and nucleoplasm) using established localization signals

By contrast, the AF3 model predicts that LIR bends round the apex of the N-lobe of GSK3 (Fig

A more recent Phase I safety trial on healthy volunteers was started in 2015 but puzzlingly, the researchers never published the results , and the trial record was marked completed with no data release