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10.2174/1389200223666220128141038 7 BaiX.YangJ.LiuG.ZhuJ.WangQ.GuW.et al

In contrast, in the process of smooth muscle contraction, under the action of substances such as norepinephrine and endothelin, the concentration of calcium ions in the cytoplasm of smooth muscle cells raises, and the GDP-binding Ras superfamily member RhoA is converted from RhoA-GDP to RhoA-GTP