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10.1161/ATVBAHA.111.227629 103

doi: 10.1038/nn.3469

Innate production of TH2 cytokines by adipose tissue-associated c- Kit + Sca-1 + lymphoid cells

In the first reaction, L-cysteine and L-glutamate are combined by the action of the enzyme called glutamate-cysteine ligase (GSHl, 6.3.2.2), generating the intermediate y-glutamylcysteine (-EC)