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Observations of hyperactive disorganized motility, commonly made by manometric recording methods in vivo, reinforce the evidence that a subset of the pool of inhibitory musculomotor neurons is tonically active and that drug-induced blockade or ablation of these neurons releases the circular muscle from the inhibitory influence [3436]

These effects can contribute to gradual, sustainable results when combined with consistent lifestyle habits

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(2) Drugs and biologicals that meet the definition of a Part D rebatable drug but, for the entire duration of the applicable period, are excluded from the definition of covered outpatient drugs as defined in section 1927(k)(2)-(4) of the Act and 447.502 of this chapter, as determined by CMS through consultation with Medicaid Drug Rebate Program staff and review of the Medicaid Drug Programs system