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Recent studies reported that activated cGAS-STING pathway reshaped the TIME, significantly induced TLS formation, and enhanced anticancer immunity in melanoma and lung carcinoma [41, 42]

Chronic Stress and Illness: Conditions like diabetes and infections consume more glutathione as the body tries to maintain balance

J Exp Bot 58:10351045 Meloni DA, Oliva MA, Martinez CA, Cambraia J (2003) Photosynthesis and activity of superoxide dismutase, peroxidase and glutathione reductase in cotton under salt stress

Mitochondria contain multiple copies of their own genome, mitochondrial DNA (mtDNA), which encodes for 13 polypeptides of the OXPHOS and respiratory chain, as well as two ribosomal RNAs and 22 transfer RNAs necessary for translation of polypeptides inside mitochondria