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If we think it is good to have these unapproved drugs available why not make a category called research chemicals, require GMP and proper quality control, call them what they are so consumers are informed, provide a little safety and efficacy information

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[12] Gastric acid-suppressing agents (proton-pump inhibitors and H-receptor antagonists) diminish dietary B12 liberation from protein complexes, a pharmacodynamic interaction that can exacerbate underlying deficiency