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In one animal study, supplementation of standard feed with MCT in juvenile male rats (10 g/kg) allowed to achieve plasma HB levels of up to 5 mM for almost 8 h with a parallel almost-2-fold decrease in plasma glucose (142)

Inhibition of mitochondrial complex I leading to NAD(+)/NADH imbalance in type 2 diabetic patients who developed late stent thrombosis: evidence from an integrative analysis of platelet bioenergetics and metabolomics

This limitation restricts the utility of peptides for conditions where oral therapy would be strongly preferred