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Accordingly, at least 80% of the amount in the stratum corneum will become available if the lag time for penetration through that tissue is less than approximately 16 h This corresponds to 5% of the typical stratum corneum turnover time of 14 days

15 Ojha S, Jailiya C

1 (panel A), free GSH disappeared within a minute after the addition of TNBS, resulting in a complex HPLC pattern showing additional molecular forms (panel B), including the formation of TNB-GSH adducts