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Protective antibodies in murine Lyme disease arise independently of CD40 ligand

I., Uthirapathy S., Ballal S., Gabble B

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The studies highlight its effects in the regulation of Th17/Treg populations [79], promoting the proliferation of CD4(+)CD29(+) cells and modulating immunosuppressive pathways [80], enhancing the polarization of the anti-inflammatory phenotype in macrophages (M2) [81]