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(2017) further supported rutins antidepressant potential by observing a dose-dependent decrease in immobility time during the tail suspension test (TST) in mice treated with rutin (Yushau et al., 2017) (Figure 3)

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In this study, we demonstrated that the transcription factor LcERF107 activated the expression of genes related to oxygen glutathione metabolism and significantly enhanced the activities of antioxidant enzymes, which led to the accumulation of ROS and reactive oxygen species in the body, thus improving the freezing tolerance of blue honeysuckles under low-temperature stress

Peptide and protein drugs: The study of their metabolism and catabolism by mass spectrometry