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Abnormal mitochondrial fission results in mitochondrial fragmentation, triggering depolarization, oxidative stress, and ultimately severe neuronal damage (Santos et al., 2015

15 Fitly, P-gp participates in the formation of cell membranes and increases the negative charges on the surface of the tumor cell membrane, which is conducive to the combination of cationic AMPs and drug-resistant tumor cell membranes, thereby better exerting anti-cancer activity

Because of that, BPC-157 should be approached as an emerging therapy, not as a proven solution for injuries or chronic pain

doi: 10.1016/j.ymeth.2013.04.005 27 SaitoTTakedaNAmiyaENakaoTAbeHSembaHet al