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Inhibitors of EMT-associated transcription factors or cytoskeletal remodelers can suppress the hybrid E-M states characteristic of DTP cells, sensitizing them to TKIs or chemotherapy, and reducing persistence (6466)

Blood-brain barrier-penetrating siRNA nanomedicine for Alzheimers disease therapy

Nature 547:453457 Wirth EK, Conrad M, Winterer J, Wozny C, Carlson BA, Roth S, Schmitz D, Bornkamm GW, Coppola V, Tessarollo L, Schomburg L, Kohrle J, Hatfield DL, Schweizer U (2010) Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration