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10.1111/apha.12365 Acta Physiol

Data from de Oliveira et al

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Abnormal mitochondrial ferroptosis is observed in the hearts of diabetic mice, mainly manifested by decreased mitochondrial membrane potential, downregulated expression of key enzymes involved in antioxidant defence (superoxide dismutase [SOD 2 ] and glutathione peroxidase 1 [GPX 1 ]) in the mitochondria, and significantly increased mitochondrial ROS levels (57)