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Variables de estudio Variables universales y clnicas Al momento de la inclusin, para cada paciente se recogieron datos demogrficos y clnicos: edad, sexo, diagnstico, gravedad valorada por APACHE II (Actue Physiology and Chronic Health Evaluation II) 17 y curso clnico mediante el clculo del SOFA (Sepsis-Related Organ Failure Assesment) 18

However, specific patient populations such as individuals with mutations in their glutathione synthesizing enzymes, AIDS patients, and cystic fibrosis patients can benefit from glutathione supplementation (Ashley, 2018)

For example, omega-6 linoleic acid supports barrier integrity and prevents transepidermal water loss, while omega-9 oleic acid reduces inflammation via activation of SIRT1, a key regulator of oxidative stress

Efficacy of ozone therapy as an add-on treatment in fibromyalgia: a randomized double-blind placebo-controlled study