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553 In another randomized, double-blind, placebo-controlled, crossover study with 70 healthy adults, a single 300 mg dose of the same mango leaf extract significantly improved performance accuracy (2.4%), episodic memory (2.8%), and visual information processing scores compared with placebo over the course of several hours

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In adults, the most frequent symptoms are abdominal pain, hepatomegaly, and laboratory abnormalities that include increased levels of transaminases and cholesterol

The mechanisms underlying how decreased VEGF levels impact neural perfusion have been postulated to involve impaired vascular regulation