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When saturated FAs such as palmitate build up, the excess lipid saturation alters the transmembrane environment and thereby activates ER stress sensors docked in the ER membrane, including IRE1 and PERK, thereby triggering pro-apoptotic responses 113,114,115,116,117,118,119

Orion Books, a division of Hachette UK, will publish the UK editions

Moreover, melatonin can enhance the heat resistance of rice seeds by enhancing the activity of antioxidant enzymes and significantly reducing the content of malondialdehyde (Yu et al., 2022)