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However, injections require clinic visits and professional administration, increasing treatment costs

TB-500 is a shortened version of Thymosin Beta-4, a naturally occurring peptide in nearly all human and animal cells

Using optogenetic neuronal stimulation, we showed that repeated neuronal stimulation in iM1 promotes behavioral recovery in a stroke mouse model, with an associated increase in cerebral blood flow, neurovascular coupling response, and an increase in neurotrophins

In preclinical mouse models, MOTS-C administration prevented body weight gain of approximately 1520% in high-fat-diet cohorts compared with untreated controls (Lee et al., 2015