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However, whether YAP1 regulates ferroptosis in CRPC cells and the underlying mechanisms are unknown

12 The Department of Gastroenterology and Clinical Research Center of Shanghai Changhai Hospital, affiliated with Naval Medical University, led by Academician Zhaoshen Li and Director Yiqi Du, has long been committed to research on H

Springer, Cham, pp 2582 Li R, Wang Q, Zhao M et al (2019) Flavonoid glycosides from seeds of Hippophae rhamnoides subsp

The explanation of the effects of xCT inhibition on the efficacy of anti-PD-1/anti-PD-L1 treatment is unknown, but its possible that, the inhibition of xCT could alter the concentration of glutamate and cystine, which might partially influence the efficacy of immune checkpoint blockade ( + T cells ( 3.3 Role of Riluzole in the blockage of glutamate secretion Glutamate transporters and exchangers are important in the regulation of the intra- and extracellular glutamate concentration