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Although K48-linked ubiquitination is the canonical signal for proteasomal degradation, the UPS exhibits remarkable versatility through alternative ubiquitin linkages and chain architectures (Fig

These findings suggested that renal tubule-specific deletion of Acsl4 reduced ferroptosis occurrence and offered protection against oxalate-induced AKI

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Inulin and metformin ameliorate polycystic ovary syndrome via anti-inflammation and modulating gut microbiota in mice