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For mTYR, H60, H84 and H93 chelate CuA, while H258, H262 and H295 chelate CuB

[2] Here is what some researchers believe about these modifications: - Position 2: The amino acid alanine is replaced with its mirror image, D-alanine

Das S, Ciombor KK, and Haraldsdottir S, et al (2020) Immune-related adverse events and immune checkpoint inhibitor efficacy in patients with gastrointestinal cancer with Food and Drug Administration-approved indications for immunotherapy Oncologist 25 (8) 669679 PMID: 31943525 PMCID: 7418359 62

Resistance [edit] Development of bacterial resistance under therapy is a frequent occurrence and makes fosfomycin unsuitable for sustained therapy of severe infections